SCIENTIFIC CORNER

Poster

ASBMR2018

Bilateral Distal Femoral Epiphyseal Defect Models for Safety Testing: A 5-Week Rat Bone Healing Study

Poster

ACT 2018

Metabolite profiling and identification in dog plasma and tissues of edasalonexent (CAT-1004), a conjugate of docosahexaenoic acid (DHA) and salicylic acid (SA)

Poster

ACT 2018

Interspecies Comparison of Embryo-fetal Data among control groups of Sprague- Dawley rats, New Zealand White rabbits and Gottingen minipigs

Poster

ACT 2018

Evaluation of Primary Hemostasis Using Bleeding Time Tests: Anatomical Sites and Species Comparison

Poster

ACT 2018

Evaluation of liver metabolism following phenobarbital treatment in the Göttingen minipig

Poster

ACT 2018

Electrolyte quantification in the aqueous and vitreous humor of common preclinical species

Poster

ACT 2018

Effects of Common Confounders on JTp and Tpe as Novel Proarrhythmia Biomarkers

Poster

ACT 2018

Characterization of EEG Morphologies During Drug-Induced Seizures and Peri-Ictal Changes in Non-Clinical Species

Poster

ACT 2018

An up to 6 Month Subcutaneous Infusion Qualification Study in Beagle Dogs

Article

Journal of Pharmacological and Toxicological Methods

A cardiovascular monitoring system used in conscious cynomolgus monkeys for regulatory safety pharmacology: Part 2: Pharmacological validation

Article

Journal of Pharmacological and Toxicological Methods

A cardiovascular monitoring system in conscious cynomolgus monkeys for regulatory safety pharmacology Part 1: Non-pharmacological validation

Article

Journal of Pharmacological and Toxicological Methods

Non-invasive measure of respiratory mechanics and conventional respiratory parameters in conscious large animals by high frequency Airwave Oscillometry

Article

Journal of Pharmacological and Toxicological Methods

The emerging role of in vitro electrophysiological methods in CNS safety pharmacology

Article

Journal of Pharmacological and Toxicological Methods

Safety pharmacology investigations on the nervous system: An industry survey

Article

Journal of Pharmacological and Toxicological Methods

Seizure liability assessments using the hippocampal tissue slice: Comparison of non-clinical species

Article

Journal of Pharmacological and Toxicological Methods

Safety pharmacology investigations in toxicology studies: An industry survey

Article

Article

Regulatory Toxicology and Pharmacology

Respiratory safety pharmacology: Positive control drug responses in Sprague–Dawley rats, Beagle dogs and cynomolgus monkeys

Article

Journal of Pharmacological and Toxicological Methods

Respiratory mechanics: Comparison of Beagle dogs, Göttingen minipigs and Cynomolgus monkeys

Article

Pharmacological and Toxicological Methods

Rat Cardiovascular Telemetry: Marginal Distribution Applied to Positive Control Drugs

Article

Sleep electroencephalographic characteristics of the Cynomolgus monkey measured by telemetry

Article

Journal of Pharmacological and Toxicological Methods

Reprint of “Effects of amphetamine, diazepam and caffeine on polysomnography (EEG, EMG, EOG)-derived variables measured using telemetry in Cynomolgus monkeys”

Article

Journal of Pharmacological and Toxicological Methods

Combined cardiopulmonary assessments with implantable telemetry device in conscious freely moving cynomolgus monkeys

Article

Journal of Pharmacological and Toxicological Methods

Functional neurotoxicity evaluation of noribogaine using video-EEG in cynomolgus monkeys

Article

Journal of Pharmacological and Toxicological Methods

Cardiac voltage-gated ion channels in safety pharmacology: Review of the landscape leading to the CiPA initiative

Article

Journal of Pharmacological and Toxicological Methods

Evaluation of a novel ECG lead placement method in telemetered freely moving cynomolgus monkeys: Assessment of an intravascular biopotential lead

Article

Journal of Pharmacological and Toxicological Methods

Cardiac contractility: Correction strategies applied to telemetry data from a HESI-sponsored consortium

Article

Journal of Pharmacological and Toxicological Methods

Video-electroencephalography in conscious non human primate using radiotelemetry and computerized analysis: Refinement of a safety pharmacology model

Article

Journal of Pharmacological and Toxicological Methods

Telemetry video-electroencephalography (EEG) in rats, dogs and non-human primates: Methods in follow-up safety pharmacology seizure liability assessments

Article

Journal of Pharmacological and Toxicological Methods

EEG in non-clinical drug safety assessments: Current and emerging considerations