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Supplemental and integrated studies

CiToxLAB – Your one-stop CRO for safety pharmacology

> ICH core battery

> Supplemental and integrated studies

> In Vitro Cardiovascular and Central Nervous System electrophysiology services

When scientific considerations necessitate supplemental testing, you can rely on our experience in drug liability evaluation and our successful track record at lifting clinical holds. We can also help leverage your toxicology studies with the addition of innovative safety pharmacology data acquisition solutions which take advantage of integrated experimental designs.

CiToxLAB offers supplemental and integrated studies spanning a range of safety pharmacology endpoints. These include tailored solutions for comprehensive pharmacodynamic investigations of your compound, and tie in well with 3Rs animal use considerations.

Supplemental and integrated studies

  • Cardiovascular monitoring in anesthetized animals
    • Left ventricular pressure
    • Central venous pressure
    • Cardiac output
    • Pulmonary arterial pressure
    • Pulmonary wedge pressure
    • Arterial blood pressure
  • Respiratory mechanics
  • Blood gases and pH
  • EEG in freely moving concious animals by telemetry
  • EEG in anesthetized animals
  • Electroretinography (ERG)
  • Gastrointestinal function
  • Renal function