Discovery Services

We’ll give you a lead in 14 days…


LeadScreenTM is your ideal program for discovery lead optimisation.

 

With LeadScreenTM:

 

  • Make your early development decisions faster
  • Lead optimization can start with as little as 20 mg
  • Get your report within 14 days
  • Choose the best candidate drug for further development

 


LeadScreenTM Genotox

 

  • Mini-Ames
  • Micronucleus in-vitro
  • Only 20 mg

 

LeadScreenTM PK

 

  • Kinetic parameters in-vivo
  • Bioavailability
  • Only 50-100 mg

 

LeadScreenTM Safety Pharmacology

 

  • QT prolongation potential in-vivo
  • ECG
  • Only 50-100 mg

 

 

LeadScreenTM Tox

 

  • Core study:
    • In-life data
    • Clinical Pathology
    • Histopathiology

 

Options:

 

  • In-vivo Genetic Toxicology
  • Genomics
    • Toxicogenomics
    • CYP induction
    • DrugMatrixTM
  • Toxicokinetics
  • Biomarkers
    • Troponine I
    • Kidney injury
  • Only 100 mg to 1 g needed